|
KMID : 0390220230340040205
|
|
Journal of Clinical Otolaryngology, Head and Neck Surgery
2023 Volume.34 No. 4 p.205 ~ p.209
|
|
|
A Case of Concomitant Occurrence of Eosinophilic Mucin Rhinosinusitis and Allergic Bronchopulmonary Aspergillosis Managed with Dupilumab after Endoscopic Sinus Surgery
|
|
Park Hye-Jin
Kim Sung-Dong
Cho Eun-Jung
Cho Kyu-Sup
|
|
|
Abstract
|
|
|
Eosinophilic mucin rhinosinusitis (EMRS) is a subtype of chronic rhinosinusitis with nasal polyps, characterized by eo- sinophilic allergic mucin produced through type 2 inflammation without fungal detection. Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterized by type 2 inflammation, continually leading to mucoid impaction in the lower airways, due to hypersensitivity reactions to inhaled Aspergillus fumigatus. Certain patients with EMRS or ABPA experience relapsing disease despite undergoing maximal treatment due to uncontrolled type 2 inflammation.
The authors report and review a case of concomitant occurrence of EMRS and ABPA managed with dupilumab. This case illustrates the potential utility of dupilumab for a broader range of conditions.
|
|
|
KEYWORD
|
|
|
Dupilumab, Eosinophilic mucin rhinosinusitis, Allergic fungal rhinosinusitis, Aspergillosis, allergic bron- chopulmonary
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|